Jubilant Biosys

Jubilant Biosys is a Contract Research and Manufacturing Organization (CRMO) that provides integrated services from early drug discovery to preclinical studies for global pharmaceutical and biopharmaceutical companies. With bases in India and Europe, we contribute to the creation of innovative therapeutics through high-quality research and development support.

Here, we will introduce in detail Jubilant Biosys' strengths in non-clinical studies, examples of disease models they possess, and specific use cases.

Jubilant Biosys' Contract Non-Clinical Testing Services Features

Addressing a wide range of disease areas

One of Jubilant Biosys's features is its ability to address a wide range of disease areas, including cancer, central nervous system disorders, metabolic diseases, pain, and inflammation. At its advanced research facilities in India and France,in vitroandin vivoWe offer a wide range of non-clinical testing services, from pharmacology studies to drug metabolism and pharmacokinetics (DMPK) studies, and GLP and non-GLP toxicology studies, flexibly meeting the diverse drug discovery needs of our customers.

An integrated approach with comprehensive facilities

Another key feature is our integrated approach, leveraging comprehensive facilities and advanced expertise. Our experienced team of scientists utilize high-performance infrastructure to deliver high-quality data, supporting rapid decision-making from the early stages of development. We go beyond simple contract testing; as a CRDMO, we offer end-to-end support, from identifying drug discovery targets to preclinical testing and even the scale-up manufacturing of active pharmaceutical ingredients, thereby facilitating a more efficient drug discovery process.

An example of a pathological model held by Jubilant Biosys

Diversein vivoPathological model

The company offers a wide range of [products/services] to thoroughly evaluate complex disease mechanisms.in vivoI own animal models.

Representative examples include pain models that evaluate chemotherapy-induced allodynia and bone cancer pain, and skin disease models for contact dermatitis and psoriasis. In addition, "metabolic disease models," including diabetes, are well-developed, supporting the efficacy evaluation of new drug candidate compounds with study designs tailored to the characteristics of each disease.

Advanced oncology models

For cancer, a key focus area, we offer a rich selection of proprietary, advanced oncology models. Specifically, evaluation systems utilizing a wide variety of cancer cell lines, including pancreatic, lung, and breast cancer, are available. By leveraging these models, which are based on past research trends, we can meticulously validate the efficacy and mechanisms of action of anticancer drugs, thereby supporting efforts to accelerate and achieve success in the development of innovative pharmaceuticals in the field of oncology.

Jubilant Biosys's Non-Clinical Study Cases

Due to the nature of being a CRDMO, strict confidentiality agreements (NDAs) are in place, and details of individual drug discovery program support are not publicly disclosed on our website. For approaches to specific disease targets or detailed case studies, please contact us directly to receive information disclosure or proposals tailored to your requirements.

Jubilant Biosys also supports the non-clinical studies of its sister company, Jubilant Therapeutics. The following are case studies featured in Jubilant Therapeutics' public disclosures.

New anti-cancer drug non-clinical study cases

We conducted non-clinical studies on "JBI-778," a novel PRMT5 inhibitor candidate for anti-cancer drugs. This compound isin vitroIn addition to demonstrating antitumor activity in preclinical studies, oral administration achieved greater than 90% tumor growth inhibition in a mouse Z-138 xenograft model%.

Furthermore, sustained exposure and substantial survival extension in the brain have been confirmed in a glioblastoma (GBM) model of the same location, showing promising data as a clinical candidate.

Jubilant Biosys Company Information

Jubilant Biosys is a global company that seamlessly supports early drug discovery research through to commercial production. Leveraging its infrastructure and expertise, it holistically supports its customers' drug development.