Biotoxtech Co.,Ltd.

Biotoxtech Co.,Ltd. is a Korean CRO(contract research organization) specializing in safety studies. The company conducts GLP-compliant non-clinical studies covering toxicity, efficacy, and pharmacokinetics. Biotoxtech operates as a direct research partner, providing contract research services without intermediaries or agents.

Features of Biotoxtech Co.,Ltd.’s Non-Clinical Testing Services

Efficacy evaluation services for disease-specific in vitro and in vivo models

Biotoxtech Co.,Ltd. has established both in vitro and in vivo models for efficacy evaluation across a wide range of disease areas, including diabetes, hypertension, dementia, osteoporosis, and liver disease.
In addition to pharmaceuticals, the company supports the acquisition of various data required for functional evaluation and regulatory approval of health foods and cosmetics.

Biotoxtech Co.,Ltd. is well-versed not only in Korean regulations but also in international guidelines and global research trends, maintaining a comprehensive non-clinical evaluation system to meet diverse client needs.

Support for juvenile animal model studies in pediatric drug development

Another distinctive feature of Biotoxtech Co.,Ltd. is its capability to conduct non-clinical safety studies using juvenile animal models.
For the evaluation of growth, development, motor activity, cognition, and toxicokinetics in pediatric drug development, the company have various established study protocols, which are corresponding to human developmental stages from birth to over 21 days of age.

Their ability to accurately capture the unique physiological responses of pediatric populations—distinct from those of adults—is one of Biotoxtech Co.,Ltd.’s key strengths.

Extensive GLP certifications and proven track record in Korea

Biotoxtech Co.,Ltd. has obtained multiple GLP certifications from Korean authorities, including the Ministry of Food and Drug Safety, the National Institute of Environmental Research, and the Rural Development Administration.
With extensive experience in toxicology, pharmacology, and metabolic studies, Biotoxtech is a highly reliable partner for companies seeking robust, reproducible non-clinical data.

Example of Biotoxtech Co.,Ltd.’s Disease Models

Diabetes model (in vitro / in vivo evaluation models for diabetes)

Biotoxtech has developed in vitro and in vivo preclinical models for diabetes, enabling comprehensive evaluation of candidate compounds through analyses of glucose regulation mechanism, insulin sensitivity, and improvements in glucose metabolism.

In addition to diabetes, the company also offers multiple experimental models and disease progression models that generate high-quality, reliable data for pharmaceutical drugs and functional materials.

Reference: Biotoxtech Co.,Ltd.( http://jpn.biotoxtech.com/pageLink.do?baseMenuNo=9910000&menuNo=9912100)

Biotoxtech Co.,Ltd. Non-Clinical Case Study

PK/TK Combined Pharmacokinetic and Toxicokinetic Study (Simultaneous Evaluation of Efficacy and Safety)

This integrated study evaluates the absorption, distribution, metabolism, and excretion (PK) of drug candidates, as well as the kinetics of toxicity onset (TK).
By analyzing both toxicity and efficacy with a focus on blood concentration—and utilizing advanced analytical techniques such as HPLC, LC/MS, and LC/MS/MS—Biotoxtech Co.,Ltd., they can deliver precise, reliable, and regulatory-compliant data.

Reference: Biotoxtech Co.,Ltd.( http://jpn.biotoxtech.com/pageLink.do?baseMenuNo=9910000&menuNo=9913100)

Biotoxtech Co.,Ltd. Company Information