Hamamatsu Pharma Research

Hamamatsu Pharma Research specializes in non-clinical studies using non-human primates (NHPs).

This page showcases key features of the company’s non-clinical capability, examples of disease models, and case studies.

We hope it serves as a useful reference when you are selecting a non-clinical CRO.

Non-clinical Model Available at Hamamatsu Pharma Research

High-precision pharmacological study using non-human primates (NHPs)

EPHamamatsu Pharma Research specializes in non-clinical models with non-human primates such as crab-eating macaques—the experimental animals most closely related to humans.

By overcoming the limitations of conventional small animal models such as mice, the company has improved the accuracy of efficacy predictions in humans.

These studies are especially reliable in areas where human-like models are essential, including central nervous system (CNS) disorders and rare diseases.

Drug discovery support using unique disease models and the PIT method

In collaboration with Hamamatsu University School of Medicine, the company provides high-precision non-clinical studies utilizing the university’s proprietary “PIT method” and can offer co-development of new model or established disease models.

Their research covers a wide range of disease areas, including exudative and atrophic age-related macular degeneration, osteoarthritis of the knee, anti-tumor drug-induced neuropathic pain, cerebral infarction, and Parkinson’s disease.

Even when a candidate drug shows limited efficacy, the obtained data can provide valuable insights for the future research and development.

Experienced researchers and full ethical accreditation

The company is equipped with teams of specialized researchers with advanced expertise in primate handling and testing.

They offer flexible work flow that allows for last-minute protocol modifications if necessary.

Hamamatsu Pharma Research is fully accredited by AAALAC International standard, ensuring the highest standards of animal welfare, ethics, and safety.

Contract Research Partners of Hamamatsu Pharma Research

No information regarding partnered organizations was found on the official website.

Case Studies of Non-clinical Trials

Pharmacological studies for central nervous system diseases

Hamamatsu Pharma Research focuses on the development of experimental models for focal cerebral ischemia (acute and chronic) and Parkinson’s disease in small animals and monkeys.
For cerebral infarction, they offer middle cerebral artery (MCA) thrombus, permanent occlusion, transient occlusion, and embolization models, which enable quantification of infarct size and functional assessments.
For Parkinson’s disease, available models include the systemic MPTP administration model and the MPTP hemiparkinsonism model.

Pharmacological studies for cardiovascular diseases

The company has developed various thrombosis models, including the PIT model (Photochemically Induced Thrombosis).
It can produce mural thrombi through balloon injury and perform quantitative evaluation using diagnostic ultrasound and MRI imaging technologies.

Company Information

Hamamatsu Pharma Research focuses exclusively on non-clinical pharmacological testing and is actively engaged in research and development within this field.