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Biocytogen Boston Corp

Table of Contents
Table of Contents

This article introduces Biocytogen Boston Corp, a biotechnology company headquartered in Beijing, China.

To expand its efforts in antibody drug development, the company has established two divisions. One is BioMice, a contract research division that provides non-clinical study support to pharmaceutical companies, biotech firms, and academic institutions. The other focuses on the discovery and development of new antibody drugs for licensing and partnership opportunities.

Features of Biocytogen Boston Corp’s Contract Non-Clinical Research Services

Comprehensive support from early-stage drug discovery to IND submission

Before a drug can enter the market, it must undergo thorough evaluation of its efficacy, safety, and mechanism of action. Biocytogen Boston Corp provides custom gene editing services, animal and cell models, and comprehensive in vivo, ex vivo, and in vitro pharmacological testing to support efficient drug discovery from the earliest stages through IND submission.

In addition, the company offers a wide selection of established animal and cell models to accelerate research timelines.

Focus on a wide range of therapeutic areas

Biocytogen Boston Corp provides solutions with diverse disease models and integrated services to advance drug development across multiple therapeutic areas. This includes immuno-oncology, oncology, autoimmune diseases, inflammatory diseases, and neurological disorders.

Operation of large-scale animal facilities

In addition to its 55,000-square-meter SPF facility in Haimen, Jiangsu Province inChina, Biocytogen Boston Corp also operates smaller facilities in Daxing, Beijing in China, and Boston, USA. The Haimen Animal Center has been AAALAC-accredited since 2016, and the Beijing Animal Center has been certified since 2021. The company’s satellite facility in Boston also complies with the same international standards.

Example of Biocytogen Boston Corp’s Disease Models

Biocytogen provides a variety of disease models across different therapeutic areas. In oncology and immuno-oncology, one of the company's proprietary models include cell line-derived xenograft (CDX) models, in which human tumor cell lines are transplanted into immunodeficient mice, as well as humanized immune checkpoint mouse models.

Many other Models are also available for respiratory diseases such as asthma and pulmonary fibrosis, and for dermatological conditions such as psoriasis and atopic dermatitis.

Biocytogen Boston Corp Non-Clinical Case Studies

No specific case studies were available on the official website.

Company Information

In addition to its headquarters in Beijing, Biocytogen Boston Corp has offices in Nantong, Jiangsu Province, and in Boston, USA.

AddressNo. 12 Baoshan South Street, Daxing Biomedical Industry Base, Daxing District, Beijing, China
Tel+86 (010) 56967680
Websitehttps://biocytogen.com/

3 Recommended Contract Research Organizations
for Non-Clinical Studies
— by Target goal and Expertise

In non-clinical development, the choice of contract research organization shapes the quality of the data and the time it takes to reach the next decision. Below, three CROs are introduced by the type of study they support: pharmacology (efficacy) studies, safety studies, and pharmacokinetic (PK/PD) studies. Each summary describes the services the company offers so that you can match a provider to your target and development objective.

Pharmacology (Efficacy) StudiesDisease-Relevant Models for
Translational Drug Evaluation
SMC Laboratories, Inc.
Reference: SMC Laboratories, Inc. official website (https://www.smccro-lab.com/)

SMC Laboratories, Inc.

SMC Laboratories is a specialized non-clinical CRO focused on in vivo pharmacology and efficacy studies using disease-relevant animal models, particularly in fibrosis, inflammation, metabolic diseases, and oncology.

Areas of Expertise
Disease-Relevant Model Portfolio

SMC Laboratories offers models covering the liver, lung, kidney, intestine, and oncology. Its portfolio includes the proprietary STAM™ model for MASH, fibrosis, and hepatocellular carcinoma.

Study Design Based on Target Biology

Study plans are developed around the target biology, mechanism of action, disease stage, and development objective. Pharmacological endpoints can be combined with histopathology, biomarkers, and disease-specific readouts.

Support from Target Validation to Proof of Concept

With experience from more than 1,000 studies for clients in 30 countries, SMC Laboratories supports programs from target validation and candidate selection through in vivo proof-of-concept studies.

Safety StudiesComprehensive Safety Assessment for
Preclinical Development
Charles River Laboratories
Reference: Charles River Laboratories official website (https://www.criver.com/)

Charles River Laboratories

Charles River provides non-clinical toxicology and safety assessment services for programs ranging from exploratory safety studies to IND-enabling development.

Areas of Expertise
General Toxicology Across Study Designs

Services include single- and repeat-dose toxicology, dose-range finding, and general toxicology studies across multiple species and administration routes.

Non-GLP and GLP Study Support

Charles River supports both non-GLP and GLP studies, allowing sponsors to progress from early safety characterization to studies intended for regulatory submissions.

Integrated IND-Enabling Safety Assessment

Toxicology studies can be integrated with toxicokinetics, clinical pathology, histopathology, and safety pharmacology to support interpretation and IND-enabling safety packages.

Pharmacokinetic (PK/PD) StudiesConnecting Drug Exposure with
Pharmacological Response
Inotiv
Reference: Inotiv official website (https://www.inotiv.com/)

Inotiv

Inotiv provides integrated PK/PD, DMPK, and bioanalytical services to characterize drug exposure and its relationship with pharmacological response.

Areas of Expertise
Pharmacokinetic Characterization

PK studies characterize exposure, half-life, clearance, and other pharmacokinetic parameters needed to understand how a candidate behaves in the selected model.

Exposure–Response Evaluation

Pharmacokinetic data can be combined with pharmacodynamic endpoints and bioanalysis to evaluate the relationship between drug exposure and pharmacological response.

Integrated DMPK and Development Support

Integrated DMPK, pharmacology, and safety information supports candidate comparison, dose selection, dosing-frequency optimization, and decisions about subsequent preclinical development.

By Therapeutic Area
Disease Animal Models
and Reviews
Proven Capability, Expertise and Track Record
Top 3 Non-Clinical CRO Services