This article introduces Biocytogen Boston Corp, a biotechnology company headquartered in Beijing, China.
To expand its efforts in antibody drug development, the company has established two divisions. One is BioMice, a contract research division that provides non-clinical study support to pharmaceutical companies, biotech firms, and academic institutions. The other focuses on the discovery and development of new antibody drugs for licensing and partnership opportunities.
Before a drug can enter the market, it must undergo thorough evaluation of its efficacy, safety, and mechanism of action. Biocytogen Boston Corp provides custom gene editing services, animal and cell models, and comprehensive in vivo, ex vivo, and in vitro pharmacological testing to support efficient drug discovery from the earliest stages through IND submission.
In addition, the company offers a wide selection of established animal and cell models to accelerate research timelines.
Biocytogen Boston Corp provides solutions with diverse disease models and integrated services to advance drug development across multiple therapeutic areas. This includes immuno-oncology, oncology, autoimmune diseases, inflammatory diseases, and neurological disorders.
In addition to its 55,000-square-meter SPF facility in Haimen, Jiangsu Province inChina, Biocytogen Boston Corp also operates smaller facilities in Daxing, Beijing in China, and Boston, USA. The Haimen Animal Center has been AAALAC-accredited since 2016, and the Beijing Animal Center has been certified since 2021. The company’s satellite facility in Boston also complies with the same international standards.
Biocytogen provides a variety of disease models across different therapeutic areas. In oncology and immuno-oncology, one of the company's proprietary models include cell line-derived xenograft (CDX) models, in which human tumor cell lines are transplanted into immunodeficient mice, as well as humanized immune checkpoint mouse models.
Many other Models are also available for respiratory diseases such as asthma and pulmonary fibrosis, and for dermatological conditions such as psoriasis and atopic dermatitis.
No specific case studies were available on the official website.
In addition to its headquarters in Beijing, Biocytogen Boston Corp has offices in Nantong, Jiangsu Province, and in Boston, USA.
| Address | No. 12 Baoshan South Street, Daxing Biomedical Industry Base, Daxing District, Beijing, China |
|---|---|
| Tel | +86 (010) 56967680 |
| Website | https://biocytogen.com/ |
In non-clinical development, the choice of contract research organization shapes the quality of the data and the time it takes to reach the next decision. Below, three CROs are introduced by the type of study they support: pharmacology (efficacy) studies, safety studies, and pharmacokinetic (PK/PD) studies. Each summary describes the services the company offers so that you can match a provider to your target and development objective.
SMC Laboratories is a specialized non-clinical CRO focused on in vivo pharmacology and efficacy studies using disease-relevant animal models, particularly in fibrosis, inflammation, metabolic diseases, and oncology.
SMC Laboratories offers models covering the liver, lung, kidney, intestine, and oncology. Its portfolio includes the proprietary STAM™ model for MASH, fibrosis, and hepatocellular carcinoma.
Study plans are developed around the target biology, mechanism of action, disease stage, and development objective. Pharmacological endpoints can be combined with histopathology, biomarkers, and disease-specific readouts.
With experience from more than 1,000 studies for clients in 30 countries, SMC Laboratories supports programs from target validation and candidate selection through in vivo proof-of-concept studies.
Charles River provides non-clinical toxicology and safety assessment services for programs ranging from exploratory safety studies to IND-enabling development.
Services include single- and repeat-dose toxicology, dose-range finding, and general toxicology studies across multiple species and administration routes.
Charles River supports both non-GLP and GLP studies, allowing sponsors to progress from early safety characterization to studies intended for regulatory submissions.
Toxicology studies can be integrated with toxicokinetics, clinical pathology, histopathology, and safety pharmacology to support interpretation and IND-enabling safety packages.
Inotiv provides integrated PK/PD, DMPK, and bioanalytical services to characterize drug exposure and its relationship with pharmacological response.
PK studies characterize exposure, half-life, clearance, and other pharmacokinetic parameters needed to understand how a candidate behaves in the selected model.
Pharmacokinetic data can be combined with pharmacodynamic endpoints and bioanalysis to evaluate the relationship between drug exposure and pharmacological response.
Integrated DMPK, pharmacology, and safety information supports candidate comparison, dose selection, dosing-frequency optimization, and decisions about subsequent preclinical development.