Anpyo Center

Effective October 1, 2024, Shinyaku Research Center, Inc. and Anpaku Center, Inc. merged, and the merged entity changed its name to TransGenic, Inc.

Below is a description of the pre-merger information.

Anpyo Center conducts a variety of pharmacological studies related to cardiovascular, allergy, anti-fatigue, and other therapeutic effects.
This section introduces the features of Anpyo Center’s non-clinical pharmacology services, examples of disease models, and related case studies.
Please use this information as a reference when selecting a contract research organization (CRO).

Features of Anpyo Center’s Non-Clinical Testing Services

Extensive Testing Experience

With over 40 years of experience, we have evaluated a wide range of disease models using genetically engineered mice and rats.
Every year, we conduct studies for more than 1,000 clients on diseases such as Parkinson’s disease and myocardial infarction, providing reliable and reproducible data.
Our trusted expertise allows us to support pharmaceutical companies and research institutions seamlessly from early-stage development to clinical trials.

Clear and Supportive Communication

We explain all study details with transparency, easy-to-understand language, minimizing technical misunderstanding.
Our policy is to provide thorough explanations of study objectives, procedures, and expected outcomes, ensuring confidence for clients with no prior non-clinical studies.

One-Stop Service

Our in-house facilities also support environmental toxicity testing. With a wide variety of studies available under one roof, all necessary tests can be completed with a single partner.

Examples of Disease Models at Anpyo Center

It is essential to go through the testing of candidate compounds in animal models that reproduce the target disease before advancing to clinical trials.

However, clinically relevant disease models may not always exist, thus there are demands for animal models with strong clinical correlation.

Below are some examples of disease models offered at Ina Research.

SCP-Induced Mouse Model

This model is used to evaluate learning and memory functions in the central nervous system.
Abnormal behaviors induced by SCP, a muscarinic anticholinergic agent, are considered to represent memory impairment in animals and are used as a preclinical indication to identify compounds that improve brain function.

Accelerated Aging Mouse Model

This lineage-specific model exhibits various aging-related disorders similar to those seen in humans, such as amyloidosis, senile osteoporosis, and learning and memory impairment.
It is widely used to study the biological mechanisms of aging, the onset of age-related diseases, and potential prevention or treatment strategies.

Middle Cerebral Artery Occlusion (MCAO) Model

We offer mice, rats, and monkeys as experimental models of stroke for developing new drugs targeting the acute phase of cerebral infarction.
Neurological symptoms, infarct formation, and changes in cerebral blood flow are observed and measured.

Examples of Non-Clinical Studies at Anpyo Center

No case studies are currently listed on the official website.

Company Information

Anpyo Center provides contract pharmacological studies for cardiovascular, allergy, anti-fatigue, and other therapeutic effects, as well as pharmacodynamic equivalence studies for generic drugs.