JOINN Laboratories (China) Co., Ltd.

JOINN Laboratories (China) Co., Ltd. is a leading China-based global contract research organization (CRO) providing integrated non-clinical research services across its own facilities. The company offers end-to-end support ranging from non-clinical studies, safety assessment, and disease model development to IND-enabling and regulatory submission support.
This section outlines the key features of JOINN Laboratories (China) Co., Ltd.’ non-clinical services, examples of disease models, and available case information.

Features of JOINN Laboratories (China) Co., Ltd.’ Contract Services for Non-Clinical Studies

High-quality material manufacturing using GMP-compliant bioreactor facilities

JOINN Laboratories (China) Co., Ltd. provides high-quality material manufacturing services utilizing GMP (Good Manufacturing Practice)-compliant bioreactor systems.Upstream processing capabilities include stainless steel bioreactors with volumes of up to 1,000 L, as well as single-use bioreactors with capacities of up to 500 L, enabling flexible optimization of cell culture processes.
These facilities support the production of preclinical materials as well as biologics and antibody therapeutics intended for clinical development, allowing JOINN to accommodate a wide range of client development needs. In combination with integrated in-process testing technologies, the company ensures robust process control and generates reliable, high-quality data.

Comprehensive IND registration and submission support

JOINN Laboratories (China) Co., Ltd.comprehensive support for Investigational New Drug (IND) registration and submission,aligned with regulatory requirements across multiple regions, including China (NMPA), the United States (FDA), and Japan (PMDA). Services cover the preparation of regulatory documentation from the non-clinical stage onward, including compilation of pharmacology and toxicology data, as well as development of clinical trial protocols and informed consent documents.
Dedicated regulatory teams develop submission strategies tailored to the specific characteristics of each compound and its development stage, streamlining the regulatory process, reducing time to approval, and enabling clients to efficiently prepare for global clinical trial initiation.

Evaluation systems compliant with international regulatory standards

JOINN Laboratories (China) Co., Ltd. conducts a broad range of safety studies in compliance with international standards, including FDA, ICH, and GLP requirements.Available studies include safety pharmacology, general toxicity, genotoxicity, and pathology assessments, as well as system-specific safety evaluations targeting cardiovascular, respiratory, and central nervous systems.
All studies are performed under standardized quality control systems, generating high-reliability data suitable for regulatory submission. Through comprehensive safety profiling and rigorous risk assessment, JOINN supports informed decision-making from the early stages of drug development.

Examples of Disease Models Available at JOINN Laboratories (China) Co., Ltd.

JOINN Laboratories (China) Co., Ltd. offersmetabolic disease models, including diet-induced obesity (DIO) models and type 2 diabetes models, for the establishment and evaluation of disease-relevant pathophysiology.In DIO models, animals such as mice fed a high-fat diet are used to reproduce human obesity and associated conditions, including insulin resistance and dysregulated lipid metabolism. Disease-related endpoints such as body weight gain, blood glucose fluctuations, and lipid profile changes can be assessed, supporting efficacy and safety evaluation of drug candidates as well as mechanistic studies.

In the field of infectious diseases,JOINN Laboratories (China) Co., Ltd. also providesanimal models, including influenza virus infection models.These models enable evaluation of antiviral efficacy, immune responses, and safety profiles of candidate therapeutics and vaccines in virus-infected animals, generating data that support drug discovery and development for infectious disease treatment and prevention.

JOINN Laboratories (China) Co., Ltd. Non-Clinical Case Study

No public nonclinical case examples are currently disclosed.

JOINN Laboratories (China) Co., Ltd. Company Information