EP Mediate Co.,Ltd.

EP Mediate Co.,Ltd. provides non-clinical (in vivo and in vitro) functional and safety evaluations, identification of active ingredients, and studies on qualitative and quantitative analytical methods. This section introduces the features of EP MEDIATE’s non-clinical studies, examples of disease models, and related case studies. Please use this information as a reference when selecting a contract research organization (CRO) for non-clinical studies.

Features of EP Mediate Co.,Ltd.’s Non-Clinical Testing Services

Extensive Experience and Network

Since 2001, EP Mediate Co.,Ltd. has specialized in the development of health and functional foods as a food-focused CRO, accumulating extensive experience in this field. The company has conducted over 1,600 commissioned clinical trials (human studies) and approximately 800 non-clinical studies. It has worked with about 500 client companies, including overseas partners, and has established a nationwide network of medical institutions and study participants across Japan.
This network enables the evaluation of effects on humans for a wide range of products, including foods, supplements, health foods, cosmetics, exercise devices, beauty equipment, and relaxation products.

Reference: EP Mediate Co.,Ltd. official website ( https://www.ep-mediate.co.jp/business_ffc.php#01 )

Wide Range of Services

EP Mediate Co.,Ltd. provides diverse contract research services, including clinical trials (human studies) for food products, basic and animal research, and studies on functional ingredients.

Expert Suppor

With renowned experts in medicine and statistics as advisors, we provide sophisticated and precise services. Also, consulting and assistance with thesis development,Total R&D supportIt is a system that can

Contract Research Partners Introduced by EP Mediate Co.,Ltd.

ITEC Labs

ITEC Labs conducts contract research that integrates genomics and molecular analysis, monkey model studies, in vivo efficacy and functional studies using small animals and cells, metabolomics analysis, and gut microbiota profiling.

EP Mediate Co.,Ltd.’s Non-Clinical Study Examples

Toxicology Studies

The company conducts a wide range of safety tests, including single and repeated dose toxicity tests, genotoxicity tests (Ames, chromosomal aberration, micronucleus), reproductive and developmental toxicity tests, carcinogenicity tests, and skin and eye irritation tests.

Efficacy Studies Using Disease Models

Efficacy studies are conducted using various animal disease models to evaluate blood pressure reduction, blood glucose control, body fat reduction, arthritis relief, cholesterol reduction, anti-allergy effects, anti-tumor effects, and improvement of hyperuricemia.

Other Tests

EP MEDIATE can accommodate specialized testing requests, including safety evaluations of cosmetics and topical agents, in vitro tests, efficacy screening using genetic analysis, special analyses, and repellency tests.

Company Information

EP MEDIATE is engaged in medical device development support, health food development support (food CRO), and in vitro diagnostic (IVD) development support businesses.