CMIC HOLDINGS Co., Ltd.

CMIC HOLDINGS Co., Ltd. leverages their experience of more than 30 years and know-how as a CRO(contract research organization) to provide customizable services to meet clients’ diverse needs. This page show-cases the key features of CMIC’s non-clinical study services, examples of disease models, and related case studies. We hope it serves as a reference when you select a CRO for non-clinical research.

Features of CMIC HOLDINGS Co., Ltd.’s Non-Clinical Study Services

High-Quality Studies

CMIC HOLDINGS Co., Ltd. conducts high-quality non-clinical studies in compliance with Good Laboratory Practice (GLP) standards. The company provides highly reliable data in pharmacodynamic and pharmacokinetic studies by evaluating the safety under strict quality control.

Extensive Experience and Expertise

With a strong track record in contract research, CMIC HOLDINGS Co., Ltd. offers flexible solutions tailored to a wide range of research needs. The company has collaborated with many pharmaceutical and biotech firms, providing extensive consulting and scientific support.

Diverse Animal Models

CMIC HOLDINGS Co., Ltd. offers a wide range of animal models for specific therapeutic areas. They have a laboratory infrastructure that allows for accurate evaluation efficacy, and new models can also be developed if requested.

Examples of Disease Models Maintained by CMIC HOLDINGS Co., Ltd.

It is essential to go through the testing of candidate compounds in animal models that reproduce the target disease before advancing to clinical trials.

However, clinically relevant disease models may not always exist, thus there are demands for animal models with strong clinical correlation.

Below are some examples of disease models offered at Ina Research.

Allergic Rhinitis Model

Guinea pigs sensitized with OVA are used to evaluate drug effects on acute/chronic nasal reactions—such as rhinitis and nasal obstruction—induced by intranasal antigen administration, as well as on inflammatory cell infiltration in the nasal cavity.
Rats can also be used for efficacy studies on increased vascular permeability in the nasal mucosa.

Asthma Model

Guinea pigs sensitized with OVA are used to examine drug effects on acute/chronic asthmatic reactions and airway obstruction induced by antigen inhalation, as well as on inflammatory cell infiltration in the airway lumen.
Mouse models are also available to investigate airway hyperresponsiveness and airway remodeling.

Non-Clinical Study Cases by CMIC HOLDINGS Co., Ltd.

No case studies are currently listed on the official website.

Corporate Information

Backed by extensive experience in non-clinical research, CMIC HOLDINGS Co., Ltd. provides comprehensive services ranging from new drug development planning to preparation of regulatory submission documents.