Nonclinical Efficacy Testing » Non-Clinical CROs and Agencies » EPS Corporation

EPS Corporation

Table of Contents

EPS Corporation conducts non-clinical studies through its consolidated subsidiary, L.S.G. Corporation. Leveraging its extensive experience and IT capabilities, the research institute provides integrated support from testing to data management. With a reliability-focused research system, EPS Corporation supports clients in achieving high-quality development outcomes.

Features of EPS Corporation’s Contract Non-Clinical Study Services

In-house non-clinical testing capabilities within the group

EPS Corporation is a contract research organization offering a wide range of non-clinical study services. Through its consolidated subsidiary, L.S.G. Corporation, EPS Corporation provides pharmacology and safety studies, among other non-clinical evaluations.

Its research facilities are designed to comply with GLP and other reliability standards, ensuring high-quality support for critical preclinical evaluation processes.

Expertise in CSV support for pharmaceuticals and medical devices

EPS Corporation offers system validation (CSV) support essential for pharmaceutical and medical device R&D to ensure data integrity in non-clinical studies. The company is also capable of supporting compliance with international regulations such as FDA 21 CFR Part 11, providing consulting aligned with global standards—including documentation for regulatory submission and operational design in accordance with GxP.

Knowledge in IT implementation for non-clinical studies

To enhance data management and reliability in non-clinical studies, EPS Corporation also focuses on IT system integration.

Based on its expertise in electronic records/electronic signatures (ER/ES), LIMS, and equipment integration, EPS provides comprehensive support from system implementation to full-scale operation. By reinforcing quality assurance frameworks through IT solutions, the company achieves both operational efficiency and data accuracy.

3 Specialized Pre-clinical CROs for Advanced Drug Discovery

Examples of disease models owned by EPS Corporation

No case studies were available on the official website.

Non-clinical study examples of EPS Corporation

No case studies were available on the official website.

EPS Corporation Company Information

Address	Tsuruya Building, 2-23 Shimomiyabicho, Shinjuku-ku, Tokyo
Tel	03-5684-7797
Website	https://www.eps.co.jp/ja/

3 Recommended Contract Research Organizations
for Non-Clinical Studies
— by Target goal and Expertise

In non-clinical development, the choice of contract research organization shapes the quality of the data and the time it takes to reach the next decision. Below, three CROs are introduced by the type of study they support: pharmacology (efficacy) studies, safety studies, and pharmacokinetic (PK/PD) studies. Each summary describes the services the company offers so that you can match a provider to your target and development objective.

Pharmacology (Efficacy) StudiesDisease-Relevant Models for
Translational Drug Evaluation

Reference: SMC Laboratories, Inc. official website (https://www.smccro-lab.com/)

SMC Laboratories, Inc.

SMC Laboratories is a specialized non-clinical CRO focused on in vivo pharmacology and efficacy studies using disease-relevant animal models, particularly in fibrosis, inflammation, metabolic diseases, and oncology.

Areas of Expertise

Disease-Relevant Model Portfolio

SMC Laboratories offers models covering the liver, lung, kidney, intestine, and oncology. Its portfolio includes the proprietary STAM™ model for MASH, fibrosis, and hepatocellular carcinoma.

Study Design Based on Target Biology

Study plans are developed around the target biology, mechanism of action, disease stage, and development objective. Pharmacological endpoints can be combined with histopathology, biomarkers, and disease-specific readouts.

Support from Target Validation to Proof of Concept

With experience from more than 1,000 studies for clients in 30 countries, SMC Laboratories supports programs from target validation and candidate selection through in vivo proof-of-concept studies.

Discuss your target and development objective with SMC Laboratories to identify an appropriate model and study design.

Safety StudiesComprehensive Safety Assessment for
Preclinical Development

Reference: Charles River Laboratories official website (https://www.criver.com/)

Charles River Laboratories

Charles River provides non-clinical toxicology and safety assessment services for programs ranging from exploratory safety studies to IND-enabling development.

Areas of Expertise

General Toxicology Across Study Designs

Services include single- and repeat-dose toxicology, dose-range finding, and general toxicology studies across multiple species and administration routes.

Non-GLP and GLP Study Support

Charles River supports both non-GLP and GLP studies, allowing sponsors to progress from early safety characterization to studies intended for regulatory submissions.

Integrated IND-Enabling Safety Assessment

Toxicology studies can be integrated with toxicokinetics, clinical pathology, histopathology, and safety pharmacology to support interpretation and IND-enabling safety packages.

Explore Charles River for integrated toxicology and IND-enabling safety assessment.

Pharmacokinetic (PK/PD) StudiesConnecting Drug Exposure with
Pharmacological Response

Reference: Inotiv official website (https://www.inotiv.com/)

Inotiv

Inotiv provides integrated PK/PD, DMPK, and bioanalytical services to characterize drug exposure and its relationship with pharmacological response.

Areas of Expertise

Pharmacokinetic Characterization

PK studies characterize exposure, half-life, clearance, and other pharmacokinetic parameters needed to understand how a candidate behaves in the selected model.

Exposure–Response Evaluation

Pharmacokinetic data can be combined with pharmacodynamic endpoints and bioanalysis to evaluate the relationship between drug exposure and pharmacological response.

Integrated DMPK and Development Support

Integrated DMPK, pharmacology, and safety information supports candidate comparison, dose selection, dosing-frequency optimization, and decisions about subsequent preclinical development.

Explore Inotiv for integrated PK/PD, DMPK, and bioanalytical support.

EPS Corporation

Features of EPS Corporation’s Contract Non-Clinical Study Services

In-house non-clinical testing capabilities within the group

Expertise in CSV support for pharmaceuticals and medical devices

Knowledge in IT implementation for non-clinical studies

Examples of disease models owned by EPS Corporation

Non-clinical study examples of EPS Corporation

EPS Corporation Company Information

3 Recommended Contract Research Organizations for Non-Clinical Studies — by Target goal and Expertise

SMC Laboratories, Inc.

Charles River Laboratories

Inotiv

3 Recommended Contract Research Organizations
for Non-Clinical Studies
— by Target goal and Expertise